Top 5 Effective Supplements for Arthritis Relief


This blog offers information on natural ways to reduce pain, improve function, and decrease swelling and stiffness for those who suffer from osteoarthritis, rheumatoid arthritis, or psoriatic arthritis and are looking for natural ways to reduce swelling and stiffness.

This article discusses the scientific evidence behind five supplements that can help with arthritis symptoms, the recommended doses, and how to choose high-quality products.

5 Effective Supplements for Arthritis Relief

1. Collagen

Collagen is the most abundant protein in our bodies and is crucial in maintaining the strength of our skin, nails, and bones. As we age, collagen formation slows down, leading to weaker joints and an increased risk of arthritis. Studies have shown that supplementing with collagen peptides or hydrolyzed collagen can lead to stronger cartilage and reduced pain and stiffness in people with osteoarthritis, especially knee osteoarthritis.

The effect of collagen peptides in patients with rheumatoid arthritis is still debatable. Collagen has anti-inflammatory properties, which can be helpful for patients with Rheumatoid arthritis. Still, there is no clear evidence of benefit, and we need more well-designed trials to understand. 

Recommended Dose

The recommended dose of collagen peptides for arthritis relief is typically 5-10 grams daily.

2. Glucosamine and Chondroitin

Glucosamine and chondroitin are natural compounds found in joint cartilage. Several studies, including the GAIT study and the MOVES trial, have shown that these supplements can relieve knee osteoarthritis pain and swelling, comparable to nonsteroidal anti-inflammatory drugs (NSAIDs) like celecoxib (Celebrex).

Recommended Dose

Many researchers recommend trying glucosamine sulfate (not hydrochloride) with or without chondroitin sulfate for knee osteoarthritis. The typical daily dose is 1,500 mg of glucosamine and 1,200 mg of chondroitin.

Is glucosamine and chondroitin safe?

Glucosamine and chondroitin are considered safe, with no serious side effects reported in studies. However, these supplements can interact with blood thinners like warfarin (Coumadin) or your blood sugars if you are diabetic, so it is best to discuss this with your doctor before taking any supplements.

3. Fish Oil / Omega3s

Fish oil is a rich source of omega-3 fatty acids with potent anti-inflammatory properties. Numerous studies have found that fish oil supplements can significantly reduce joint pain, stiffness, and swelling in people with rheumatoid arthritis, lupus, gout, osteoarthritis, and psoriatic arthritis. Fish oil may also reduce the need for NSAIDs in patients with back or neck pain.

Recommended Dose

The recommended dose of fish oil for arthritis relief is typically 2-4 grams of EPA/DHA daily.

Is fish oil safe?

Some fish oil products might be contaminated with mercury. Choose a fish oil supplement that has a sustainability certification, such as from the Marine Stewardship Council.

You should take fish oil with a meal, as other dietary fats improve the absorption of omega-3 fatty acids. Fish oil can interact with your blood thinner,  blood pressure, or contraceptive medications.

4. Boswellia

Boswellia is an herbal extract from the Boswellia tree containing Boswellic acids, which have potent anti-inflammatory properties. Studies have shown that boswellia can reduce pain and improve joint function in people with osteoarthritis without serious side effects.

Recommended Dose

The recommended dose of Boswellia for osteoarthritis is typically 100 mg per day.

Is Boswellia safe?

Be careful, as Boswellia may increase the side effects of other drugs, including antidepressants, anti-anxiety medications, ibuprofen, and immunosuppressants.  

5. Turmeric (Curcumin)

Turmeric is a spice commonly used in Asian cuisine. Its active ingredient, curcumin, has potent anti-inflammatory properties. Studies have shown that curcumin can reduce pain and inflammation in people with osteoarthritis and rheumatoid arthritis, comparable to NSAIDs like diclofenac and ibuprofen but with fewer side effects.

Recommended Dose

The recommended dose of curcumin for arthritis relief is typically 1,000-1,500 mg per day, with an enhanced absorption formula containing piperine (black pepper extract).

Is Turmeric/ curcumin safe?

Be careful that High doses of turmeric/ curcumin can act as a blood thinner or worsen the effect of blood thinners like coumadin/ warfarin.

How to Choose High-Quality Supplements?

When selecting supplements, looking for products certified by third-party organizations like NSF or USP is crucial. These certifications ensure that the product contains the claimed ingredients and doses and is free from contaminants like heavy metals or toxins.

Always Consult Your Doctor

Before starting any new supplement regimen, it’s essential to consult with your healthcare provider, especially if you have any underlying medical conditions or are taking medications. Some supplements may interact with certain drugs or have side effects, so it’s important to discuss your options with a professional. Have you tried any of these supplements for arthritis relief? Let us know in the comments below which worked best for you, and share your experience.

Experience Holistic Arthritis Care with Rheumatologist OnCall

While supplements can be a helpful addition to your arthritis management plan, working closely with healthcare professionals to develop a comprehensive, holistic approach tailored to your specific needs is essential.

At Rheumatologist OnCall, we understand the complexities of arthritis and the importance of addressing the condition from multiple angles. Our experienced rheumatologists are dedicated to providing personalized, holistic care through our convenient telemedicine platform.

By scheduling a virtual consultation with Rheumatologist OnCall, you’ll have access to:

  • Expert guidance on incorporating supplements safely and effectively into your treatment plan
  • Customized medication management strategies
  • Lifestyle and dietary recommendations
  • Mind-body therapies and stress management techniques
  • Regular monitoring and adjustments to your care plan as needed

Don’t let arthritis pain and discomfort hold you back any longer. Schedule your virtual consultation with a rheumatologist on call today to take the first step towards comprehensive, holistic care.

Experience the Convenience of Telemedicine

With Rheumatologist OnCall, you can receive high-quality arthritis care from the comfort of your own home or wherever is most convenient for you. Our telemedicine platform ensures you access expert care without the hassle of traveling to a physical clinic.

In addition to personalized care, Rheumatologist OnCall is committed to empowering you with the knowledge and support you need to manage your arthritis actively. Our team will provide you with educational resources, answer your questions, and guide you every step of the way. Schedule your virtual consultation with a Rheumatologist on Call today.


All content shared on this site is for informational purposes only and is not a substitute for medical advice, diagnosis, or treatment. This site and its services do not constitute the practice of medicine. You should always talk to your health care provider for diagnosis and treatment regarding your specific medical needs. We don’t represent that any of the products or services offered through this site are safe, appropriate, or effective for you. We advise you to always seek the advice of a physician or other qualified health care provider regarding personal health or medical conditions. If you know or suspect you have a medical problem, contact a qualified healthcare professional immediately. If you’re experiencing a medical emergency, call 911.

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